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Extra info for Collection of Problems in Illustration of the Principles of Theoretical Mechanics
7». lln[(V -13)/24]. (Vo = 37 ml; Vrnax = 116 ml; Vrnin = 13 ml, myocardial volume = 113 ml (mean values from , Table 2). b Comparison between wall stress and cellular restoring stress. 07In(R[liSL + SLo]lLo) where R equals the mean slope of the distribution between lengthening and shortening sarcomeres shown in Fig. 3. This minimal restoring force does not consider the true restoring force within the sarcomere which is likely to be larger. 9 J-tm in the unstressed volume of the heart (Vo).
Fabiato A, Fabiato F (1976) Dependence of calcium release, tension generation and restoring forces on sarcomere length in skinned and cardiac cells. Eur J Cardiol 4 (Suppl): 13-27 8. Ter Keurs HEDJ, Rijnsburger WH, van Heuningen R (1980) Restoring forces and relaxation in rat cardiac muscle. Eur Heart J 1 (Suppl A): 67-80 9. Harding SE, Viscovo G, Kirby M, Jones MS, Gurden J, Poole-Wilson PA (1988) Contractile response of isolated adult rat and rabbit cardiac myocytes to isoproterenol and calcium.
The simple fact that ventricular filling pressure is reduced at end systolic volume is not sufficient to demonstrate that there has been an increase in the potential energy stored elastically inthe wall of the heart! Computations based on the negative pressure-volume relations obtained when ventricular filling is prevented by programmed mitral occlusion  show that volume dependence of intraventricular negative pressure requires an increase in the restoring stresses of the wall (Fig. 4a). 5% of the peak active tension that the isolated muscle can produce, and 5% of end systolic wall stress.